Potential statin-drug interactions: prevalence and clinical significance

Potential statin-drug interactions: prevalence and clinical significance

BACKGROUND Statins are cholesterol-lowering drugs widely used for cardiovascular prevention. Although safe when used alone, in combination with other drugs the likelihood of adverse drug reactions increases significantly. The exposure of the Bulgarian population to coprescriptions leading to potential statin-drug interactions is currently unknown. OBJECTIVE The aim of this study was to invest...

Clinical decision making on statin drug interactions.

Potential Drug Interactions in War-Injured Veterans

Drug-drug interaction (DDI) is one of the most important problems in the treatment of patients suffering from different chronic intractable diseases. The war-injured veterans are one of the groups that are prone to chronic refractory diseases. This investigation was conducted on war-injured veterans treated in a multi-disciplinary clinic in Tehran. Using Poisson model, a total of 150 patients w...

The potential for drug interactions with statin therapy in Ireland.

BACKGROUND Seven percent of acute hospital admissions result from adverse drug reactions, of which 25% are due to drug interactions. Adverse effects of statin drugs occur in 3% of patients, mainly due to co-prescribing with other lipid-lowering agents or agents that alter their metabolism. AIM The aim of this study was to investigate co-prescribing of the frequently-used statin medications wi...

Prevalence of Potential Drug-Drug Interactions in Hospitalized Surgical Patients

The objective of this study is to estimate the prevalence and describe the characteristics of pDDIs (potential drug-drug interactions) in medical prescriptions of hospitalized surgical patients. In this cross-sectional study, we analyzed 370 medical prescriptions from the surgery unit of a Mexican public teaching hospital. The identification and classification of potential drug-drug interaction...